Don’t Buy Topical Niacinamide Skin Cream Until You Read This... Some of the most popular acne cream products today contain either antimicrobials or retinoids. Antimicrobials inhibit or kill acne causing bacteria. Retinoids, which are made from vitamin A, stop the formation of blackheads, whiteheads, and unclog the pores. Below are some examples of these. Topical Antimicrobials · Clindamycin is a semi-synthetic antibiotic. Clindamycin lessens inflammation and reduces acne. Clinical tests have proven Clindamycin to be well tolerated and safe. However, it may cause side effects such as skin dryness or irritation. It can decrease the bacterial resistance that often occurs when antibiotics are used. · Erythromycin has both antimicrobials and anti-inflammatory properties. Acne cream preparations that combine erythromycin and benzoyl peroxide have been proven to be very effective. Side effects include dryness and irritation of the treated area. It can also decrease the bacterial resistance from antibiotic use. Topical Retinoids · Adapalene is a synthetic retinoid that unclogs pores and has moderate to potent anti-inflammatory properties. Dryness and minor skin irritation are possible occurences with use. · The first retinoid produced for topical (applied to skin) use was Tretinoin. Tretinoin is a natural retinoid which over time unclogs pores, and helps keep them unclogged. Redness, itching, and burning, are some of the side effects observed in users. Topical Niacinamide Skin Cream (also called Nicotinamide) After Vitamin-A derived retinoids, the most recent revolutionary treatment for acne comes from a substance called niacinamide. It is made from the B vitamin niacin. In a New York University study, acne treatment and niacinamide was the subject, and 76 people were tested for the acne healing effects of 1% clindamycin gel compared to 4% Niacinamide gel. The preparations were used on moderate to inflammatory acne, twice daily for eight weeks. RESULTS...68% of the Clindamycin patients improved, compared to 82% of Niacinamide treated patients. Niacinamide is the preferred choice because it doesn't diminish bacterial resistance, as Clindamycin is widely known for. Acnessential, a 4% Niacinamide cream, is one of the most effective acne cream products in the market today. Some advantages are... · It is natural and safe to use for as long as you need it. · It will not make your skin develop bacterial resistance unlike most antimicrobials. · It is ideal if you have dry, sensitive skin and cannot tolerate retinoids well. Additionally, a 4% Niacinamide cream (such as Acnessential brand) can be applied alongside retinoids and antibiotics, or on its own.